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©2005 Baishideng Publishing Group Inc.
World J Gastroenterol. Feb 21, 2005; 11(7): 964-969
Published online Feb 21, 2005. doi: 10.3748/wjg.v11.i7.964
Published online Feb 21, 2005. doi: 10.3748/wjg.v11.i7.964
Table 2 Ductal infiltrations, lymph node metastasis and Tie-1, 2 and Ang-1, 2 and 4 expressions in invasive colorectal adenocarcinoma (n = 76), n (%).
n | Tie-1 | Tie-2 | Ang-1 | Ang-2 | Ang-4 | |||||||||||
- | + | ++ | - | + | ++ | - | + | ++ | - | + | ++ | - | + | ++ | ||
Invasive carcinoma | 76 | 5 (6.6) | 15 (19.7) | 56 (73.7) | 2 (2.6) | 18 (23.7) | 56 (73.7) | 6 (7.9) | 17 (22.4) | 53 (69.7) | 4 (5.3) | 17 (22.4) | 55 (72.4) | 13 (17.1) | 19 (25.0) | 44 (57.9) |
Desmoplastic stromal reaction | NS | P = 0.039383 | NS | NS | NS | |||||||||||
Slight | 13 | 2 (15.4) | 2 (15.4) | 9 (69.2) | 1 (7.7) | 5 (38.5) | 7 (53.8) | 4 (30.8) | 2 (15.4) | 7 (53.8) | 1 (7.7) | 4 (30.8) | 8 (61.5) | 4 (30.8) | 0 (0.0) | 9 (69.2) |
Moderate | 47 | 2 (4.3) | 11 (23.4) | 34 (72.3) | 1 (2.1) | 11 (23.4) | 35 (74.5) | 2 (4.3) | 12 (25.5) | 33 (70.2) | 3 (6.4) | 10 (21.3) | 34 (72.3) | 8 (17.0) | 15 (31.9) | 24 (51.1) |
Extensive | 16 | 1 (6.3) | 2 (12.5) | 13 (81.3) | 0 (0.0) | 2 (12.5) | 14 (87.5) | 0 (0.0) | 3 (18.8) | 13 (81.3) | 0 (0.0) | 3 (18.8) | 13 (81.3) | 1 (6.3) | 4 (25.0) | 11 (68.8) |
Venous invasion | NS | P = 0.005992 | NS | P = 0.018168 | NS | |||||||||||
Present | 35 | 1 (2.9) | 7 (20.0) | 27 (77.1) | 0 (0.0) | 4 (11.4) | 31 (88.6) | 2 (5.7) | 6 (17.1) | 27 (77.1) | 1 (2.9) | 4 (11.4) | 30 (85.7) | 5 (14.3) | 9 (25.7) | 21 (60.0) |
Absent | 41 | 4 (9.8) | 8 (19.5) | 29 (70.7) | 2 (4.9) | 14 (34.1) | 25 (61.0) | 4 (9.8) | 11 (26.8) | 26 (63.4) | 3 (7.3) | 13 (31.7) | 25 (61.0) | 8 (19.5) | 10 (24.4) | 23 (56.1) |
Lymphatic invasion | P = 0.033356 | P = 0.001326 | P = 0.039066 | NS | NS | |||||||||||
Present | 60 | 1 (1.7) | 12 (20.0) | 47 (78.3) | 0 (0.0) | 11 (18.3) | 49 (81.7) | 3 (5.0) | 12 (20.0) | 45 (75.0) | 2 (3.3) | 13 (21.7) | 45 (75.0) | 7 (11.7) | 16 (26.7) | 37 (61.7) |
Absent | 16 | 4 (25.0) | 3 (18.8) | 9 (56.3) | 2 (12.5) | 7 (43.8) | 7 (43.8) | 3 (18.8) | 5 (31.3) | 8 (50.0) | 2 (12.5) | 4 (25.0) | 10 (62.5) | 6 (37.5) | 3 (18.8) | 7 (43.8) |
Lymph node metastasis | NS | NS | NS | NS | NS | |||||||||||
Present | 27 | 1 (3.7) | 4 (14.8) | 22 (81.5) | 1 (3.7) | 4 (14.8) | 22 (81.5) | 1 (3.7) | 8 (29.6) | 18 (66.7) | 1 (3.7) | 6 (22.2) | 20 (74.1) | 4 (14.8) | 11 (40.7) | 12 (44.4) |
Absent | 49 | 4 (8.2) | 11 (22.4) | 34 (69.4) | 1 (2.0) | 14 (28.6) | 34 (69.4) | 5 (10.2) | 9 (18.4) | 35 (71.4) | 3 (6.1) | 11 (22.4) | 35 (71.4) | 9 (18.4) | 8 (16.3) | 32 (65.3) |
- Citation: Nakayama T, Hatachi G, Wen CY, Yoshizaki A, Yamazumi K, Niino D, Sekine I. Expression and significance of Tie-1 and Tie-2 receptors, and angiopoietins-1, 2 and 4 in colorectal adenocarcinoma: Immunohistochemical analysis and correlation with clinicopathological factors. World J Gastroenterol 2005; 11(7): 964-969
- URL: https://www.wjgnet.com/1007-9327/full/v11/i7/964.htm
- DOI: https://dx.doi.org/10.3748/wjg.v11.i7.964