Inhibitory effect of fluvastatin on ileal ulcer formation in rats induced by nonsteroidal antiinflammatory drug

Table 2 Reducing power of HMG-CoA reductase inhibitors(mean±SD).

HMG-CoA reductase inhibitor	Dose (mmol/L)	Absorbance at 510 nm (as the reducing power)
Solvent only	0	0.182±0.019
Fluvastatin	0.01	0.545±0.0162
Pravastatin	0.01	0.182±0.021
Atorvastatin	0.01	0.308±0.0162
Gallic acid	0.005	0.709±0.0101

The intensity of the absorbance at 510 nm reflected antioxidative activity as the reducing power.

¹Gallic acid was not a HMG-CoA reductase inhibitor and used as a positive control of this test.

²Significantly different from the solvent at P<0.0001 (ANOVA).