Combination of telomerase antisense oligonucleotides simultaneously targeting hTR and hTERT produces synergism of inhibition of telomerase activity and growth in human colon cancer cell line

Figure 3 Apoptosis induced by treatment with ASODN in SW480 cells. A: Cells were transfected with various agents (1: blank control, 2: s-hTR, 3: s-hTERT, 4: Oligofectamine^TM, 5: anti-hTR, 6: anti-hTERT, 7: anti-hTR+anti-hTERT) for 72 h; B: Cells were transfected with ASODN for 24, 48, 72 h, respectively (mean±SD of three experiments).