Basic Research
Copyright ©2005 Baishideng Publishing Group Inc.
World J Gastroenterol. Feb 14, 2005; 11(6): 778-784
Published online Feb 14, 2005. doi: 10.3748/wjg.v11.i6.778
Table 1 Frequency of LOH and MSI of tumor suppressor genes in sporadic colorectal cancers.
MarkerInformative /Total (%)LOH/Informative (%)MSI No./Total (%)
NM23-H1125/207 (60.4)43/125 (31.6)4/164 (2.4)
APC121/207 (58.5)56/121 (47.8)10/151 (6.6)1
Tp53.alu103/207 (49.8)67/103 (65.0)1/140 (0.7)
HPC1127/207 (61.4)15/127 (11.8)6/192 (3.1)
D8S25489/207 (43.0)46/89 (51.7)5/161 (3.1)
DCC98/207 (47.3)63/98 (64.3)3/144 (2.1)
hMSH2153/207 (73.9)24/153 (15.7)19/183 (10.4)1
hMLH199/207 (47.8)26/99 (26.3)11/181 (6.1)
MET91/207 (44.0)27/91 (29.7)7/180 (3.9)
Tp53.pcr1580/207 (38.6)31/80 (38.8)5/174 (2.9)
MYCL1110/207 (53.1)38/110 (34.5)5/169 (3.0)
Bat-2530/207 (14.5)3/30 (10)22/204 (9.8)1
Bat-2641/207 (19.8)4/41 (4.4)15/203 (7.4)1
Mfd1533/207 (15.9)2/33 (7.2)9/205 (4.4)1