Fumagillin treatment of hepatocellular carcinoma in rats: An in vivo study of antiangiogenesis

Table 4 Comparison of MetAP-2 mRNA, Bcl-2 mRNA, telomerase mRNA and telomerase activity among the 3 groups of rats at wk 24.

Parameters	Group			P value
	A (n = 3)	B (n = 5)	C (n = 5)	A vs B	A vs C	B vs C
MetAP-2 mRNA	0.34	0.5	0.58	0.025	0.025	0.047
(0.32-0.36)	(0.33-0.70)	(0.40-0.73)
Bcl-2 mRNA	0	0.45	0.38	0.024	0.608	0.072
(0-0.19)	(0.22-0.63)	(0-0.42)
Telomerase mRNA	0.3	0.43	0.34	0.025	0.655	0.016
	(0.29-0.32)	(0.35-0.47)	(0.29-0.37)
Telomerase	47.6	225	203.5	0.025	0.025	0.046
Activity (%)	(46-71)	(187-310)	(94-292)

Non-parametric test: Mann-Whitney and Kruskal-Wallis tests.