Role of PGI2 in the formation and maintenance of hyperdynamic circulatory state of portal hypertensive rats

Table 3 Effects of L-NNA and INDO on systemic and splanchnic hemodynamics (mean±SD).

Group	Vehicle (n = 23)	L-NNA (n = 21)	Indo (n = 22)	Heparin (n = 24)
FPP (mmHg)
SO	6.93±0.35	7.29±0.39	7.07±0.35	7.06±0.39
IHPH	10.29±0.39a	8.75±0.46ac	9.28±0.57ac	9.25±0.65ac
PHPH	13.71±0.49a	10.05±0.45ac	11.57±0.53ac	11.07±0.79a
PVI (mL/min)
SO	2.35±0.27	1.06±0.20c	1.63±0.17c	1.57±0.31c
IHPH	3.83±0.64a	2.34±0.50ac	2.16±0.59c	2.05±0.62ac
PHPH	7.37±1.56a	3.71±0.53ac	3.77±0.81ac	2.35±0.25ac
SVR (mmHg/mL·min)
SO	58.06±6.95	96.18±13.71c	85.56±8.13c	99.36±20.26c
IHPH	32.96±5.09a	67.83±14.33ac	74.75±19.34c	68.51±22.26ac
PHPH	16.39±3.23a	36.21±5.21ac	37.52±8.10ac	54.85±6.71ac

^aP<0.05 vs SO;

^cP<0.05 vs control.