Role of PGI2 in the formation and maintenance of hyperdynamic circulatory state of portal hypertensive rats

Table 2 Effects of L-NNA and INDO on systemic hemodynamics (mean±SD).

Group	Vehicle (n = 23)	L-NNA (n = 21)	Indo (n = 22)	Heparin (n = 24)
MAP (mmHg)
SO	141.86±3.02	159.29±1.98c	145.86±3.72	157.33±3.77c
IHPH	134.00±1.83a	161.50±6.14c	161.14±4.45ac	137.88±2.17a
PHPH	130.29±1.89a	142.50±4.37ac	147.71±2.75c	138.29±4.39ac
CI (mL/min)
SO	28.46±0.58	25.34±2.22c	27.20±0.61	23.52±0.72c
IHPH	32.03±1.34a	25.03±1.76c	28.66±1.63c	28.39±2.25a
PHPH	33.19±0.66a	28.13±0.51ac	29.62±1.16ac	26.67±0.66ac
TPR (mmHg/mL·min)
SO	4.99±0.13	6.33±0.60c	5.36±0.13	6.70±0.33c
IHPH	4.19±0.18a	6.48±0.53c	5.64±0.42c	4.88±0.36a
PHPH	3.93±0.06a	5.07±0.19ac	5.00±0.33ac	5.18±0.21ac

^aP<0.05 vs SO;

^cP<0.05 vs control.