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©2005 Baishideng Publishing Group Inc.
World J Gastroenterol. Feb 7, 2005; 11(5): 665-671
Published online Feb 7, 2005. doi: 10.3748/wjg.v11.i5.665
Published online Feb 7, 2005. doi: 10.3748/wjg.v11.i5.665
Table 8 Mutagenicity in mice after bicyclol treatment.
| Group | Dosage (mg/kg) | n | MNPCE (‰) | P/N | P value | |
| Control | 6 | 2.2±0.04 | 100/56 | 1.8 | ||
| Bicyclol | 750 | 6 | 1.8±0.09 | 135/65 | 2.1 | >0.05 |
| 1500 | 6 | 2.5±0.14 | 126/74 | 1.7 | >0.05 | |
| 3000 | 6 | 1.7±0.08 | 130/70 | 1.9 | >0.05 | |
| Cyclophosphamide | 50 | 6 | 38.2±3.0 | 100/250 | 0.4 | <0.001 |
- Citation: Liu GT, Li Y, Wei HL, Lu H, Zhang H, Gao YG, Wang LZ. Toxicity of novel anti-hepatitis drug bicyclol: A preclinical study. World J Gastroenterol 2005; 11(5): 665-671
- URL: https://www.wjgnet.com/1007-9327/full/v11/i5/665.htm
- DOI: https://dx.doi.org/10.3748/wjg.v11.i5.665