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©2005 Baishideng Publishing Group Inc.
World J Gastroenterol. Feb 7, 2005; 11(5): 665-671
Published online Feb 7, 2005. doi: 10.3748/wjg.v11.i5.665
Published online Feb 7, 2005. doi: 10.3748/wjg.v11.i5.665
Table 7 Mutagenicity of bicyclol in bacteria (revertants/plate) (mean±SD).
| (mg/plate) | TA97 | TA102 | |||
| 0 | 0 | 0 | 0 | ||
| Bicyclol | 0 | 86±15 | 130±15 | 227±15 | 272±12 |
| 10 | 68±8 | 111±1 | 237±13 | 230±10 | |
| 100 | 80±1 | 116±20 | 259±33 | 304±40 | |
| 500 | 57±14 | 120±6 | 236±16 | 279±5 | |
| 1000 | 88±8 | 140±4 | 237±35 | 344±18 | |
| 5000 | 80±4 | 88±1 | 259±23 | 153±2 | |
| 9-aminoacridine | 0.2 | 938±10 | |||
| 2AF 10 | 1736±509 | ||||
| DMC 20 | |||||
| MMS 2 mL | 1606±48 | ||||
| Vp16 1 mg | 1270±37 | ||||
- Citation: Liu GT, Li Y, Wei HL, Lu H, Zhang H, Gao YG, Wang LZ. Toxicity of novel anti-hepatitis drug bicyclol: A preclinical study. World J Gastroenterol 2005; 11(5): 665-671
- URL: https://www.wjgnet.com/1007-9327/full/v11/i5/665.htm
- DOI: https://dx.doi.org/10.3748/wjg.v11.i5.665