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©2005 Baishideng Publishing Group Inc.
World J Gastroenterol. Feb 7, 2005; 11(5): 665-671
Published online Feb 7, 2005. doi: 10.3748/wjg.v11.i5.665
Published online Feb 7, 2005. doi: 10.3748/wjg.v11.i5.665
Organ weightmg/100g BW | Sex | Control | Bicyclol (mg/kg) | ||
150 | 300 | 600 | |||
Heart | M | 308±38 | 300±42 | 310±74 | 360±70 |
Liver | 2960±310 | 3120±610 | 3200±810 | 3300±700 | |
Lung | 570±120 | 620±280 | 580±160 | 700±180 | |
Kidney | 670±70 | 660±120 | 700±180 | 580±270 | |
Spleen | 160±30 | 170±40 | 170±43 | 140±45 | |
Thymus | 60±20 | 60±20 | 60±17 | 45±18 | |
Pituitary | 3±4 | 2±1 | 2±1 | 2±1 | |
Adrenal | 20±10 | 24±30 | 14±3 | 16±4 | |
Prostate | 110±30 | 120±30 | 109±29 | 110±40 | |
Seminal | 250±80 | 240±80 | 250±55 | 260±66 | |
Testis | 1150±160 | 1120±180 | 1040±301 | 1130±296 | |
Heart | F | 350±40 | 360±38 | 380±40 | 370±41 |
Liver | 3200±330 | 3300±220 | 3300±210 | 3300±290 | |
Lung | 970±320 | 890±280 | 700±80 | 680±291 | |
Kidney | 810±110 | 820±100 | 810±140 | 770±130 | |
Spleen | 220±44 | 210±36 | 240±34 | 320±54b | |
Thymus | 102±36 | 67±23b | 53±24b | 120±88 | |
Pituitary | 5±2 | 3±1 | 5±2 | 12±15 | |
Adrenal | 29±4 | 26±4 | 29±3 | 51±8 | |
Uterus | 173±50 | 147±48 | 163±31 | 158±57 | |
Ovary | 39±19 | 34±24 | 37±3 | 47±25 |
- Citation: Liu GT, Li Y, Wei HL, Lu H, Zhang H, Gao YG, Wang LZ. Toxicity of novel anti-hepatitis drug bicyclol: A preclinical study. World J Gastroenterol 2005; 11(5): 665-671
- URL: https://www.wjgnet.com/1007-9327/full/v11/i5/665.htm
- DOI: https://dx.doi.org/10.3748/wjg.v11.i5.665