Increased expression of mitogen-activated protein kinase and its upstream regulating signal in human gastric cancer

Table 3 Expression of ERK-1, ERK-2, ERK-3, p38 and MEK-1 in metastatic lymph nodes (mean±SD).

Items	n	IOD value	t	P
ERK-1
Metastatic lymph nodes	14	195734.7±70508.8
Primary site		210423.7±74207.3	0.608	0.554b
Normal mucosa		155862.3±79052.8	1.453	0.170a
ERK-2
Metastatic lymph nodes	14	186959.5±80801.8
Primary site		211155.1±64116.8	0.893	0.388b
Normal mucosa		127092.4±56585.6	2.579	0.023a
ERK-3
Metastatic lymph nodes	14	140323.2±120532.0
Primary site		98732.1±54021.3	1.261	0.230b
Normal mucosa		50032.9±58937.8	3.116	<0.001a
P38
Metastatic lymph nodes	12	96866.8±76857.3
Primary site		99740.6±38279.6	0.202	0.844b
Normal mucosa		77784.4±30367.0	0.797	0.442a
MEK-1
Metastatic lymph nodes	12	133353.9±42374.3
Primary site		101112.5±39124.0	2.203	0.05b
Normal mucosa		77431.9±31282.1	4.235	<0.001a

^aP<0.05 vs normal mucosa;

^bP>0.05 vs primary site.