Increased expression of mitogen-activated protein kinase and its upstream regulating signal in human gastric cancer

Table 2 Relationship between ERK1/2 expression and clinicopathological characteristics in poorly differentiated gastric cancers (mean±SD).

Items	n	ERK1			ERK2
		T:N ratio1	F (t)	P	T:N ratio1	F (t)	P
TNM stage
I, II	11	1.01±0.33	2.505	0.022	1.24±0.40	2.297	0.03
III, IV	22	2.64±3.01			2.05±1.54
Lymph node involvement
+	24	2.49±2.91	2.421	0.023	1.98±1.49	2.191	0.036
-	9	1.03±0.36			1.24±0.44
Serosa invasion
+	26	2.39±2.82	2.428	0.022	1.95±1.44	2.585	0.015
-	7	1.01±0.35			1.14±0.36
Tumor size
<5 cm	19	1.97±2.30	0.323	0.749	1.72±1.31	0.309	0.76
>5 cm	14	2.27±2.96			1.86±1.39
Borrmann classification
I	5	1.27±0.53	1.42	0.257	0.96±0.22	1.169	0.338
II	22	2.17±1.64			2.96±3.27
III	12	1.30±0.68			1.02±0.37
IV	3	1.38±0.19			1.59±0.20

¹Average ratio of IOD_tumor: IOD_normals.