Tumor necrosis factor-α-induced protein 1 and immunity to hepatitis B virus

Figure 3 TNF-αIP1 shares significant homology with some human, mouse, and C elegan proteins, having common K+ channel tetramerization/POZ domain. A: Phylogenetic analysis of evolutionary distance of the protein sequences. The protein sequences were analyzed by the Growtree program provided by the GCG package. Kimura distance was adopted as the distance correction method. B: Amino acid sequence alignment of TNF-αIP1 (A41784) with mouse Edp1 protein (AAC78826), human MSTP028 protein (NP_114160), PDIP1 (AAL14962), human REN protein (XP_208568), and four C elegan K+ channel family members and with highest homology to TNF-αIP1 (NP_499312, NP_494320, NP_494476 and NP_494315). Black line: K+ channel tetramerization/POZ domain.