Possible involvement of leptin and leptin receptor in developing gastric adenocarcinoma

Table 1 Expression of leptin and ob-R in gastric cancer and precancerous lesions

	n	Leptin					Ob-R					Dualexpression ofleptinand
				+	++	++				++	+++	ob-R
		-	+	+	+	++	-	+	++	+	+	n	(%)
Intestinal	30	5	4	5	17	0	4	5	7	14	0	25	(83.3)
metaplasia
Gastric	90	6	12	28	39	0	9	15	25	35	4	79	(87.7)
dysolasia
Gastric	90	25	9	16	16	24	24	9	22	12	25	75	(83.3)
cancer

For comparison of positive percentage for dusl expression of loptin and ob-R among (1)intestinal metaplsia (2)gastric dysplasia (3)gastric carcinoma, (1)vs(2) χ² = 0.3864, P=0.5351; (1)vs(3) χ² = 0.3864, P = 1.000; (2)vs(3) χ² = 0.7193, P = 0.3964