Phagocytic and oxidative burst activity of neutrophils in the end stage of liver cirrhosis

Table 2 Phagocytic and oxidative burst activity of neutrophils, level of soluble form of adhesive molecules and TNFα in liver cirrhosis patients (mean±SD)

	Liver cirrhosis			Healthy
	Total	Child–Pugh B	Child–Pugh C
Oxidative burst
Percentage of neutrophils with oxidative burst after PMA stimulation (%)	98.3±1.2	98.4±1.5	98.2±1.6	98.8±2.8
MIF oxidative burst after PMA stimulation	42.7±14.6b	44.3±10.1b	41.1±12.6b	50.2±13.3
Percentage of neutrophils with oxidative burst after E. coli stimulation (%)	94.0±4.8	93.0±4.1	94.0±3.8	92.2±3.7
MIF oxidative burst after E. coli stimulation	24.7±7.1b	25.1±8.1b	22.2±5.1b	29.7±6.6
Phagocytic activity
Percentage of neutrophils phagocytizing of E. coli	93.0±3.3	92.9±4.3	93.8±2.3	92.5±4.3
MIF phagocytosis E. coli	20.0±3.9	19.8±4.1	21.0±2.8	19.0±5.8
Soluble form of adhesion molecules and TNFα
sICAM-1 (ng/mL)	852±331b	788±343b	892±293b	254±74
sVCAM-1 (ng/mL)	2 937±1 591b	2 637±1 291b	3 297±1 490b	510±248
sP-selectin (ng/mL)	101±180b	98±140b	104±162b	124±58
sE-selectin (ng/mL)	136±89b	120±68b	148±58b	49±21
sL-selectin (ng/mL)	1 209±364	1 206±314	1 211±344	1 209±291
TNFα (pg/mL)	2.94±1.43b	2.64±1.33b	2.99±1.02b	1.58±0.22

^bP<0.01 vs healthy subjects (Mann–Whitney U test).