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©2005 Baishideng Publishing Group Inc.
World J Gastroenterol. Dec 28, 2005; 11(48): 7631-7638
Published online Dec 28, 2005. doi: 10.3748/wjg.v11.i48.7631
Published online Dec 28, 2005. doi: 10.3748/wjg.v11.i48.7631
Table 4 Viral loads and immunological data in different RANTES-403, RANTES-28 and RANTES-IN1.1 genoytpes. Data are given as [median (range)]. Statistically significant differences are indicated by index numbers
| RANTES-403 | HCV-Infection | HIV-Infection | HIV/HCV-Infection | ||||||
| G/G(N = 71) | G/A(N = 39) | A/A(N= 2) | G/G(N= 42) | G/A(N = 38) | A/A(N = 5) | G/G(N = 86) | G/A(N = 31) | A/A(N = 3) | |
| HCV-Load | 10.8 | 4.2 | 39.0 | - - - | - - - | - - - | 13.8 | 14.0 | 1.6 |
| x 106 copies/mL | (n.d.-126.5) | (n.d.-56.6) | (n.d.-39.8) | (0.2-178.9) | (0.6-150.5) | (0.4-6.8) | |||
| HIV-Load | - - - | - - - | - - - | 455 | 380 | <80 | 550 | 770 | 9900 |
| x 103 copies/mL | (<80-830 000) | (<80-50 000) | (<80-990) | (<80-210 000) | (<80-50 000) | (2 400-27 000) | |||
| CD4 count | 683 | 621 | 916 | 353.5 | 348.5 | 300 | 302 | 279 | 293 |
| cells/µL | (171-2 039) | (282-1 544) | (787-1 045) | (51-1 111) | (5-1 142) | (28-629) | (6-1 219) | (106-651) | (149-331) |
| CD8 count | 496.5 | 499 | 581.5 | 918.5 | 927 | 1 099 | 792 | 968.5 | 675 |
| cells/µL | (62-1 653) | (185-1 183) | (425-738) | (202-1 717) | (88-2 152) | (382-1 421) | (39-2 466) | (319-3 056) | (465-895) |
| RANTES-28 | C/C (N = 108) | C/G (N = 4) | G/G (N = 0) | C/C (N = 74) | C/G (N = 9) | G/G (N = 0) | C/C (N = 112) | C/G (N = 4) | G/G (N = 0) |
| HCV-Load | 8.4 | 38.3 | - - - | - - - | - - - | - - - | 13.5 | 22.3 | - - - |
| x 106 copies/mL | (n.d.-126.5) | (29.9-39.8) | (0.2-178.9) | (0.4-45.8) | |||||
| HIV-Load | - - - | - - - | - - - | 310 | <80 | - - - | 560 | 2 150 | - - - |
| x 103 copies/mL | (<80-830 000) | (<80-3 700) | (<80-210 000) | (400-91 000) | |||||
| CD4 count | 662 | 916 | - - - | 355 | 330 | - - - | 293 | 220 | - - - |
| cells/µL | (171-2 039) | (443-1 305) | (10-1 142) | (141-637) | (13-1 219) | (149-651) | |||
| CD8 count | 499 | 581.5 | - - - | 942.5 | 636 | - - - | 828 | 602.5 | - - - |
| cells/µL | (62-1 653) | (338-739) | (202-2 152) | (362-1 997) | (39-3 056) | (397-2 401) | |||
| RANTES-IN1.1 | T/T (N = 87) | T/C (N = 25) | C/C (N = 0) | T/T (N = 53) | T/C (N = 30) | C/C (N = 1) | T/T (N = 93) | T/C (N = 27) | C/C (N = 1) |
| HCV-Load | 9.6 | 6.2 | - - - | - - - | - - - | - - - | 13.5 | 14.2 | 1.6 |
| x 106 copies/mL | (n.d.-126.5) | (0.4-56.6) | (0.2-178.9) | (0.4-150.5) | |||||
| HIV-Load | - - - | - - - | - - - | 600 | <80 | 990 | 735 | 560 | 9 900 |
| x 103 copies/mL | (<80-830 000) | (<80-38 000) | (<80-210 000) | (<80-91 000) | |||||
| CD4 count | 662 | 702 | - - - | 353 | 342 | 629 | 294 | 242 | 331 |
| cells/µL | (171-2 039) | (392-1 305) | (51-1 142) | (10-1 028) | (6-1 219) | (110-651) | |||
| CD8 count | 501 | 497 | - - - | 936.5 | 927 | 1 421 | 792 | 1 034 | 675 |
| cells/µL | (62-1 653) | (191-1 119) | (202-1 717) | (362-2 152) | (39-2 466) | (319-3 056) | |||
- Citation: Ahlenstiel G, Iwan A, Nattermann J, Bueren K, Rockstroh JK, Brackmann HH, Kupfer B, Landt O, Peled A, Sauerbruch T, Spengler U, Woitas RP. Distribution and effects of polymorphic RANTES gene alleles in HIV/HCV coinfection – A prospective cross-sectional study. World J Gastroenterol 2005; 11(48): 7631-7638
- URL: https://www.wjgnet.com/1007-9327/full/v11/i48/7631.htm
- DOI: https://dx.doi.org/10.3748/wjg.v11.i48.7631