Distribution and effects of polymorphic RANTES gene alleles in HIV/HCV coinfection – A prospective cross-sectional study

Table 3 Distribution of RANTES-403, RANTES-28 and RANTES IN1.1 genotypes and allele frequencies

RANTES-403 (%)	G/G	G/A	A/A	Statistics	[A]-allele frequency (%)	Statistics
HCV	71 (63.4)	39 (34.8)	2 (1.8)	vs HIV P = 0.077	19.2	vs HIV P = 0.047
(n = 112)
HIV	42 (49.4)	38 (44.7)	5 (5.9)		28.2
(n = 85)
HCV/HIV	86 (71.7)	31 (25.8)	3 (2.5)	vs HIV P = 0.005	15.4	vs HIV P = 0.002
(n = 120)
Controls	77 (70.6)	31 (28.4)	1 (0.9)	vs HIV P = 0.004	15.1	vs HIV P = 0.002
(n = 109)
RANTES-28 (%)	C/C	C/G	G/G	Statistics	[G]-allele frequency	Statistics
HCV	108 (96.4)	4 (3.6)	0 (0.0)	vs HIV P = 0.078	1.8	vs HIV P = 0.083
(n = 112)
HIV	74 (89.2)	9 (10.8)	0 (0.0)		5.4
n = 83
HCV/HIV	112 (96.6)	4 (3.4)	0 (0.0)	vs HIV P = 0.045	1.7	vs HIV P = 0.048
(n = 116)
Controls	103 (94.5)	6 (5.5)	0 (0.0)	vs HIV P = 0.186	2.8	vs HIV P = 0.195
(n = 109)
RANTES-In1.1 (%)	T/T	T/C	C/C	Statistics	[C]-allele frequency	Statistics
HCV	87 (77.7)	25 (22.3)	0 (0.0)	vs HIV P = 0.054	12.6	vs HIV P = 0.041
(n = 112)
HIV	53 (63.1)	30 (35.7)	1 (1.2)		19
(n = 84)
HCV/HIV	93 (76.9)	27 (22.3)	1 (0.8)	vs HIV P = 0.101	12	vs HIV P = 0.066
(n = 121)
Controls	86 (78.9)	22 (20.2)	1 (0.9)	vs HIV P = 0.052	11	vs HIV P = 0.038
(n = 109)