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©2005 Baishideng Publishing Group Inc.
World J Gastroenterol. Dec 21, 2005; 11(47): 7457-7460
Published online Dec 21, 2005. doi: 10.3748/wjg.v11.i47.7457
Published online Dec 21, 2005. doi: 10.3748/wjg.v11.i47.7457
Figure 1 Concentration of 5-ASA and Ac-5-ASA in serum (◆), urine (■), feces (○), liver homogenates (△), stomach contents (◇), small intestinal contents (▲), cecal contents (□), colonic contents (×) after the oral administration of 50 mg/kg 5-ASA or α-CyD-5-ASA (equivalent to 50 mg/kg 5-ASA) to rats.
A: Concentration of 5-ASA after oral administration of 5-ASA; B: concentration of Ac-5-ASA after oral administration of 5-ASA; C: concentration of 5-ASA after oral administration of 10 α-CyD-5-ASA; D: concentration of Ac-5-ASA after oral administration of α-CyD-5-ASA.
- Citation: Zou MJ, Cheng G, Okamoto H, Hao XH, An F, Cui FD, Danjo K. Colon-specific drug delivery systems based on cyclodextrin prodrugs: In vivo evaluation of 5-aminosalicylic acid from its cyclodextrin conjugates. World J Gastroenterol 2005; 11(47): 7457-7460
- URL: https://www.wjgnet.com/1007-9327/full/v11/i47/7457.htm
- DOI: https://dx.doi.org/10.3748/wjg.v11.i47.7457