Combined carriership of TLR9 -1237C and CD14 -260T alleles enhances the risk of developing chronic relapsing pouchitis

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 11, Issue 46

This Article

Citation of this article

Corresponding Author of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

All Articles published online

Item

Count

PDF

274

HTML

2291

Tables (1-4)

211

Sum=2776

Dec 14, 2005 (publication date) through Nov 7, 2024

Times Cited of This Article

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Rapid Communication

World J Gastroenterol. Dec 14, 2005; 11(46): 7323-7329
Published online Dec 14, 2005. doi: 10.3748/wjg.v11.i46.7323

Table 3 Genotypes of the CD14, CARD15, TLR4, TLR9, and IRAKM gene polymorphisms in subgroups of patients with IPAA and controls

Polymorphisms	Genotype	Controls	No pouchitis	Infrequent pouchitis	Chronic relapsing pouchitis
		n = 224 (%)	n = 79 (%)	n = 43 (%)	n = 35 (%)
CD14–260 C>T	CC	55 (24.6)	24 (30.4)	11 (25.6)	7 (20)
	CT	102 (45.5)	34 (43)	21 (48.8)	22 (62.9)
	TT	67 (29.9)	21 (26.6)	11 (25.6)	6 (17.1)
CARD15 3020InsC	WT/WT	218 (97.3)	77 (97.5)	43 (100)	34 (97.1)
	WT/InsC	6 (2.7)	2 (2.5)	0 (0)	1 (2.9)
	InsC/InsC	0 (0)	0 (0)	0 (0)	0 (0)
TLR4 +896 A>G	AA	208 (92.9)	73 (92.4)	38 (88.4)	33 (94.3)
	AG	16 (7.1)	5 (6.3)	5 (11.6)	2 (5.7)
	GG	0 (0)	1 (1.3)	0 (0)	0 (0)
TLR9–1237 T>C	TT	158 (70.5)	52 (65.8)	34 (79.1)	19 (54.3)
	TC	60 (26.8)	24 (30.4)	9 (20.9)	14 (40)
	CC	6 (2.7)	3 (3.8)	0 (0)	2 (5.7)
TLR9 +2848 G>A	GG	40 (17.9)	20 (25.3)	9 (20.9)	6 (17.1)
	GA	104 (46.4)	38 (48.1)	22 (51.2)	16 (45.7)
	AA	80 (35.7)	21 (26.6)	12 (27.9)	13 (37.2)
IRAKM +22148G>A	GG	181 (80.8)	64 (81)	33 (76.7)	28 (80)
	GA	42 (18.8)	14 (17.7)	7 (16.3)	7 (20)
	AA	1 (0.4)	1 (1.3)	3 (7)	0 (0)

Citation: Lammers K, Ouburg S, Morré S, Crusius J, Gionchetti P, Rizzello F, Morselli C, Caramelli E, Conte R, Poggioli G, Campieri M, Peña A. Combined carriership of TLR9 -1237C and CD14 -260T alleles enhances the risk of developing chronic relapsing pouchitis. World J Gastroenterol 2005; 11(46): 7323-7329
URL: https://www.wjgnet.com/1007-9327/full/v11/i46/7323.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i46.7323