Human leukocyte antigen class II DQB1*0301, DRB1*1101 alleles and spontaneous clearance of hepatitis C virus infection: A meta-analysis

Table 3 Effect of DQB1*0301 allele on self-limiting HCV infection

Study	Spontaneous resolutionn/N	Persistent infectionn/N	OR (random)95%CI
Alric	21/25	28/91	11.81 (3.71, 37.61)
Minton	18/35	33/135	3.27 (1.51, 7.07)
Cramp	26/49	10/55	5.09 (2.10, 12.33)
Mangia	17/33	42/143	2.56 (1.18, 5.53)
Thursz 1	39/85	47/170	2.22 (1.29, 3.82)
Thursz 2	25/57	37/152	2.43 (1.28, 4.61)
Fanning	25/78	18/67	1.28 (0.63, 2.64)
Alric	38/59	45/157	4.50 (2.39, 8.50)
Vejbaesya	24/43	18/57	2.74 (1.20, 6.22)
Thio	49/200	71/374	1.38 (0.92, 2.09)
Azocar	6/40	13/72	0.80 (0.28, 2.30)
Spada	4/10	15/24	0.40 (0.09, 1.81)
Total (95%CI)	292/714	377/1 497	2.36 (1.62, 3.43)

Test for heterogeneity: χ² = 33.33, df = 11 (P = 0.0005), I² = 67.0%. Test for overall effect: Z = 4.48 (P<0.00001).