Human leukocyte antigen class II DQB1*0301, DRB1*1101 alleles and spontaneous clearance of hepatitis C virus infection: A meta-analysis

Table 2 Effect of DRB1*1101 allele on self-limiting HCV infection

Study	Spontaneous resolutionn/N	Persistent infectionn/N	OR (random)95%CI
Alric	10/25	10/102	6.13 (2.18, 17.22)
Minton	11/35	11/135	5.17 (2.01, 13.27)
Cramp	9/49	6/55	1.84 (0.60, 5.60)
Mangia	7/35	24/149	1.30 (0.51, 3.32)
Thursz 1	26/85	29/170	2.14 (1.16, 3.94)
Thursz 2	14/57	15/152	2.97 (1.33, 6.65)
Fanning	4/68	4/64	0.94 (0.22, 3.92)
Alric	20/59	25/170	2.97 (1.50, 5.91)
Vejbaesya	2/43	3/57	0.88 (0.14, 5.50)
Thio	15/200	24/374	1.18 (0.61, 2.31)
Azocar	4/40	11/72	0.62 (0.18, 2.08)
Spada	2/10	2/24	2.75 (0.33, 22.92)
Total (95%CI)	124/706	164/1 524	2.02 (1.56, 2.62)

Test for heterogeneity: χ² = 19.38, df = 11 (P<0.05), I² = 43.2%. Test for overall effect: Z = 5.30 (P<0.00001).