Effect of oral Lactococcus lactis containing endostatin on 1, 2-dimethylhydrazine-induced colon tumor in rats

Table 2 Colon tumor incidence, classification, multiplicity, tumor volume, and stage in rats treated with DMH with or without endostatin (mean±SD)

Treatment		Incidence	Adenoma	Carcinoma	Multiplicity	Tumor volume	Duke's stage
	n	n (%)	n (%)	n (%)	number	mm3	A	B	C
DMH+endostatin	10	10(100)	5 (50)	5 (50)	2.50±1.80	2.35±1.84	1	4	-a
DMH+L lactis	10	9(90)	2 (22)	7 (78)	2.67±1.47	2.54±2.00	4	6	-a
DMH	10	10 (100)	5 (50)	5 (50)	4.00±2.96	4.31±4.56	2	-	3

^aP<0.05 vs DMH-treated rats.