Anti-Saccharomyces cerevisiae antibody titers are stable over time in Crohn’s patients and are not inducible in murine models of colitis

Table 3 Effect of the CD clinical characteristics on the following parameters: ASCA IgG and IgA positivity and change in IgG and IgA ASCA titers. Results are expressed as P-values of the mean-difference tests or as correlation coefficients (c)

Clinical characteristics	ASCA IgG	ASCA IgA	∆IgG	∆IgA
Correlation with age	c = –0.140	c = 0.198	c = –0.340	c = –0.197
Male vs female	0.881	0.881	0.089	0.571
Disease Location
Colonic vs non-colonic	0.667	0.169	0.203	0.289
Ileal vs non-ileal	0.285	0.285	0.032a	0.395
Fistular vs Non-fistular disease	0.152	0.075	0.499	0.907
Medical therapy
Azathioprine	0.881	0.881	0.749	0.375
Infliximab	0.233	0.233	0.87	0.844
5-ASA compounds	0.806	0.233	0.903	0.491
Oral steroids	0.512	0.385	0.475	0.531
None of the above medical
therapy vs medical therapy	0.285	0.577	0.438	0.117

^aP<0.05.