Expression of Ki-67, p53, and K-ras in chronic pancreatitis and pancreatic ductal adenocarcinoma

Figure 3 H&E and immunohistochemical staining of pancreatic cancer. A: Moderate to poorly differentiated pancreatic adenocarcinoma with desmoplastic background. H&E stain, ×200; B: Immunohistochemical staining using CEA monoclonal antibody shows positive reaction in the cytoplasms of tumor cells. DAB and hematoxylin counter stain, ×200; C: Ki-67 monoclonal antibody shows significantly increased proliferation of nuclei of tumor cells. DAB and hematoxylin counter stain, ×200; D: Intense nuclear immunohistochemical staining of p53 in an invasive pancreatic adenocarcinoma. AEC and hematoxylin counter stain, ×200.