Association between cag-pathogenicity island in Helicobacter pylori isolates from peptic ulcer, gastric carcinoma, and non-ulcer dyspepsia subjects with histological changes

Table 6 Frequency of atrophy, metaplasia, and dysplasia in chronic gastritis subjects

Clinical	Acute	Chronic gastritis
status (n)	gastritis (%)	Superficial	Gastritis with	Gastritis with	Gastritis with
		gastritis	atrophy (%)	metaplasia (%)	dysplasia (%)
DU (58)	0	52 (89.7)	2 (3.4)	4 (6.9)	0
GU (46)	0	9 (19.6)	13 (28.3)	14 (30.4)	10 (21.7)
NUD (56)	0	51 (91.1)	5 (8.9)	0	0
Total (160)	0	112 (70)	20 (12.5)	18 (11.25)	10 (6.25)

For atrophy, DU vs GU combination is highly significant at 0.1% level (P<0.001), GU vs NUD is significant at 1% level (P<0.01) and DU vs NUD combination is not significant at 1% level. For metaplasia, DU vs GU, GU vs NUD combinations are highly significant at 0.1% level (P<0.001) and DU vs NUD combination is significant at 5% level (P<0.05). For dysplasia, DU vs GU, GU vs NUD combinations are highly significant at 0.1% level (P<0.001) and DU vs NUD combination is not significant at any level.