Characteristics of patients with columnar-lined Barrett’s esophagus and risk factors for progression to esophageal adenocarcinoma

Table 2 Risk factors associated with the development of adenocarcinoma in patients with CLE; results of multivariable regression analysis

Risk factors	Odds ratio	95%CI for Odds ratio	P
Age ≥60 yr	1.65	0.75–3.64	0.216
Male sex	5.12	2.04–12.84	0.0005
Regular alcohol use	1.15	0.46–2.90	0.76
NSAIDs	1.41	0.68–2.93	0.352
Esophagitis	0.28	0.13–0.57	0.0006
Esophageal stricture	4.37	2.02–9.45	0.0002

CLE – columnar lined esophagus; NSAIDs – non-steroidal anti-inflammatory drugs