Herpes simplex virus type 1 in peptic ulcer disease: An inverse association with Helicobacter pylori

Table 2 Association between H pylori and HSV-1 in patients with peptic ulcer

	H pylori (+), %	H pylori (–)	P	Odds ratio (95%CI)
Peptic ulcer	76/90 (84.4)	14/90	0.002	3.7 (1.6–8.1)
Controls	30/50 (60)	20/50
Gastric ulcer	25/34 (73.5)	9/34	0.036	3.67 (1.1–12.11)
Duodenal ulcer	51/56 (91.1)	5/56
HSV-1 (+)	19/28 (67.9)	9/28	0.009	5.4 (1.61–18.11)
HSV-1 (–)	57/62 (91.9)	5/62
HSV-1 (+)/GU	4/11 (36.4)	7/11	0.002	18.37 (2.75–122.94)
HSV-1 (–)/ GU	21/23 (91.3)	2/23
HSV-1 (+)/Duodenal ulcer	15/17 (88.2)	2/17
HSV-1(–)/Duodenal ulcer	36/39 (92.3)	3/39	0.634	-

HSV-1 (+)/gastric ulcer, patients with gastric ulcer positive for HSV-1; HSV-1 (–)/gastric ulcer, patients with gastric ulcer negative for HSV-1; HSV-1 (+)/duodenal ulcer, patients with duodenal ulcer positive for HSV-1; HSV-1 (–)/duodenal ulcer, patients with duodenal ulcer negative for HSV-1; CI, confidence interval.