Differential effects of glutamate receptor antagonists on dorsal horn neurons responding to colorectal distension in a neonatal colon irritation rat model

Figure 2 Effect of AP7 (0. 01 mmoL) on dorsal horn neuronal responses to CRD in control or CI rats. Rate histograms illustrate the responses of a dorsal horn neuron isolated from a control rat (A) and of another neuron isolated from a CI rat (B) before (grey) and after (black) spinal administration of AP-7 (0.01 mmoL). Horizontal bars indicate the timing and duration (10 s) of CRD (20- 80 mmHg).