Rapid Communication
Copyright ©2005 Baishideng Publishing Group Inc.
World J Gastroenterol. Nov 7, 2005; 11(41): 6525-6529
Published online Nov 7, 2005. doi: 10.3748/wjg.v11.i41.6525
Table 2 Relationship between different HBV genotypes and YMDD mutations, clinical types of CHB, ALT, and HBV DNA level, HBe system
GenotypesnRate of YMDDClinical type of CHBClinical test
mutation (%)Mild and moderateSevereCHB (%)Abnormal rateHBV DNA >105HBeAg(+)/HBeAb(–)
CHB (%)of ALT (%)copies/mL (%)
B98 (88.9)1 (11.1)3 (33.3)4 (44.4)7/2
C156 (40.0)4 (26.7)11 (73.3)8 (53.3)9 (60.0)10/5
D337 (21.2)14 (42.4)19 (57.6)23 (69.7)22 (66.7)23/10
CD4315 (34.9)19 (44.2)24 (55.8)32 (74.4)30 (69.8)28/15
CB166 (37.5)9 (56.3)7 (43.7)9 (56.3)10 (62.5)12/4
BD154 (26.7)7 (46.7)8 (53.3)8 (53.3)9 (60.0)9/6
Non-A–F258 (32.0)15 (60.0)10 (40.0)12 (48.0)10 (40.0)8/17
χ22.78811.2729.8587.44812.841
P>0.05>0.05>0.05>0.05<0.05