Genistein inhibits invasive potential of human hepatocellular carcinoma by altering cell cycle, apoptosis, and angiogenesis

Table 1 Effects of genistein on cell cycle progression in Bel 7402 cell line (mean±SD)

Treatment	Cell cycle phase			Apoptosis (%)
	G0/G1 (%)	G2/M (%)	S (%)
Control	64.58 ± 8.46	0.78 ± 0.02	34.64 ± 1.36	0.47 ± 0.01
Genistein 5 μg/mL	71.74 ± 4.46	2.75 ± 0.03b	25.50 ± 2.28b	1.02 ± 0.06a
Genistein 10 μg/mL	75.27 ± 6.12ac	6.37 ± 0.08d	18.36 ± 1.53b	2.12 ± 0.12b

^aP < 0.05 vs control;

^bP < 0.01 vs control;

^cP < 0.05 vs 5 μg/mL genistein;

^dP < 0.01 vs control and 5 μg/mL genistein. vs control and 5 μg/mL genistein.