Cytochrome P450 2E1 high activity polymorphism in alcohol abuse and end-organ disease

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Nov 7, 2005 (publication date) through Nov 8, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 7, 2005; 11(41): 6445-6449
Published online Nov 7, 2005. doi: 10.3748/wjg.v11.i41.6445

Table 3 Alcoholic subgroup figures and analyses

	Normal controls n = 208 (%)	Alcoholic controls n = 67 (%)	Alcoholic end organ disease n = 172 (%)	Fisher’s exact test
Presence of
insertion polymorphism	12 (5.8)	3 (4.5)	2 (1.2)	P = 0.045
Genotype for
insertion polymorphism
Heterozygote	12 (5.8)	3 (4.5)	1 (0.6)	P = 0.011
Homozygote	0 (0.0)	0 (0.0)	1 (0.6)

Citation: Cartmell MT, Schulz HU, O’Reilly DA, Yang BM, Kielstein V, Dunlop SP, Halangk W, Demaine AG, Kingsnorth AN. Cytochrome P450 2E1 high activity polymorphism in alcohol abuse and end-organ disease. World J Gastroenterol 2005; 11(41): 6445-6449
URL: https://www.wjgnet.com/1007-9327/full/v11/i41/6445.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i41.6445