Pioglitazone, a specific ligand of peroxisome proliferator-activated receptor-gamma, protects pancreas against acute cerulein-induced pancreatitis

Table 1 Histology findings in the pancreas after treatment with various doses of pioglitazone alone or in combination with cerulein infused s.c. to induce pancreatitis

	Edema	Leukocyte infiltration	Vacuolization of acinar cells
Control	0	0	0
Pioglitazone 10 mg/kg	0	0	0
Pioglitazone 20 mg/kg	0	0	0
Pioglitazone 50 mg/kg	0	0	0
Pioglitazone 100 mg/kg	0	0	0
Cerulein	2/3	2	2/3
Pioglitazone 10 mg/kg+cerulean	2/3	1/2	2
Pioglitazone 20 mg/kg+cerulean	2	1	0.5
Pioglitazone 50 mg/kg+cerulean	1/2	0/1	1
Pioglitazone 100 mg/kg+cerulean	1	1	1