Prevention of core cell damage in isolated islets of Langerhans by low temperature preconditioning

Figure 8 Re-warmed islets with diameters <100 μm (A), 100-200 μm (B), 200-300 μm (C), and >300 μm (D) after a 7-d culture at 26 °C during an additional 7-d culture at 37 °C. Islets cultured only at 37 °C served as controls. The 7-d culture preconditioning at 26 °C was effective to reduce core cell damage of islets with diameter >100 μm under 37 °C culture conditions. ^aP<0.05 vs Controls.