Herbal cardiotonic pills prevent gut ischemia/reperfusion-induced hepatic microvascular dysfunction in rats fed ethanol chronically

Figure 1 Effects of chronic ethanol consumption and/or Cardiotonic Pill (CP) on the number of stationary leukocytes, plasma ALT activities, plasma endotoxin concentration, and plasma TNF-α concentration after gut I/R. Each group consisted of five animals. ^aP<0.05 vs control, ^cP<0.05 vs Control+I/R, ^eP<0.05 vs ethanol+I/R. A: Effects of chronic ethanol consumption and/or CP on the number of stationary leukocytes in each region (the midzonal and pericentral regions) (panel A) and the entire (combined) liver lobule (panel B) after 30 min of gut ischemia and 60 min of reperfusion; B: Effects of chronic ethanol consumption and/or CP on plasma ALT activities at 6 h after gut I/R; C: The effects of chronic ethanol consumption and/or CP on plasma endotoxin concentration after 30 min of gut ischemia and 60 min of reperfusion; D: The effects of chronic ethanol consumption and/or CP on plasma TNF-α concentration after 30 min of gut ischemia and 60 min of reperfusion.