Noninvasive estimation of liver fibrosis and response to interferon therapy by a serum fibrogenesis marker, YKL-40, in patients with HCV-associated liver disease

Figure 4 Serum levels of type IV collagen, PIIIP, HA and YKL-40 before and 6 months after IFN therapy in NVR and SVR patient groups. The box represents the interquartile range. The whiskers indicate the highest and lowest values, and the line across the box indicates the median value. The levels of all serum markers without type IV collagen 6 mo after IFN treatment were lower than those before IFN treatment in SVR group (^aP<0.05), while only YKL-40 levels decreased in NVR group (^aP<0.05).