Pituitary adenylate cyclase activating-peptide and its receptor antagonists in development of acute pancreatitis in rats

Table 2 Histological scoring (action of PACAP) (mean±SE).

Group	Hemorrhage	Parenchymal necrosis	Vacuolization	Inflammation
Caerulein-induced pancreatitis			1.67±0.60	2.5±0.22
Sodium taurocholate-induced pancreatitis	1.5±0.67	2.5±0.49	0.5±0.49	3
PACAP 5 μg			0.33±0.33	0.17±0.17
PACAP 10 μg		0.17±0.17	0.67±0.49	1.33±0.61
PACAP 15 μg			0.33±0.33	1.5±0.67
PACAP 30 μg		0.17±0.17	0.83±0.54	1.5±0.5
Sodium taurocholate+PACAP 5 μg	1.67±0.49	2.67±0.33	2±0.63	3
Sodium taurocholate +PACAP 10 μg	2±0.63	2.5±0.5	1.5±0.56	3
Caerulein+PACAP 15 μg	1.5±0.5	2±0.63	2.5±0.22	1.67±0.60
Caerulein+PACAP 30 μg	1.83±0.60	2.17±0.31	2.33±0.49	2.17±0.48