Serum leptin levels and insulin resistance are associated with gallstone disease in overweight subjects

Table 3 Univariated analysis of conditional logistic regression, stratified by BMI

Variable	BMI <30			BMI ≥30
	OR	95%CI	P	OR	95%CI	P
Age (yr)	1.20	0.97-1.49	0.09	0.93	0.68-1.26	0.62
Leptin (ng/mL)	1.06	0.99-1.13	0.09	0.91	0.81-1.03	0.15
Insulin (μU/mL)	1.09	1.02-1.16	0.01	0.94	0.86-1.03	0.17
HOMA-IR	1.33	1.06-1.68	0.02	0.85	0.61-1.17	0.32
T-chol (mmol/L)	1.0	0.99-1.00	0.32	1.02	0.99-1.05	0.27
LDL (mmol/L)	1.0	0.99-1.01	0.51	1.01	0.98-1.05	0.39
HDL (mmol/L)	0.99	0.97-1.01	0.44	1.02	0.95-1.09	0.66
NHDL (mmol/L)	1.0	0.99-1.01	0.44	1.02	0.99-1.05	0.30
TGC (mmol/L)	1.0	1.0-1.0	0.86	1.0	1.0-1.01	0.3
Leptin ≥9.78 ng/mL	2.25	1.08-4.69	0.03	0.12	0.01-1.0	0.05
Leptin terciles (ng/mL)	1.67	1.03-2.69	0.04	0.14	0.02-0.98	0.05
Insulin ≥20 μU/mL Non		convergence		0.47	0.12-1.88	0.29
HOMA-IR >2.5	1.46	0.75-2.83	0.27	0.44	0.11-1.84	0.26
T-chol ≥6.21 mmol/L	0.86	0.42-1.74	0.67	3.88	0.38-39.5	0.25
LDL ≥4.14 mmol/L	1.06	0.55-2.04	0.87	1.50	0.36-630	0.58
HDL <1.03 mmol/L	1.26	0.66-2.41	0.49		Non convergence
NHDL ≥4.91mmol/L	1.07	0.54-2.13	0.84	0.78	0.07-8.88	0.84
TGC ≥1.7 mmol/L	1.09	0.60-1.99	0.77	3.03	0.76-12.1	0.12

OR, odds ratio; 95%CI, 95% confidence intervals; BMI, body mass index; T-chol, total cholesterol; LDL, low-density cholesterol; HDL, high density cholesterol; NHDL, non-HDL cholesterol; TGC, triglycerides.