Value of endoscopic methylene blue and Lugol's iodine double staining and detection of GST-Π and telomerase in the early diagnosis of esophageal carcinoma

Table 6 Expressions of GST-Π and telomerase activity in esophageal carcinoma and premalignant lesions

	Normal epithelium		Hyperplasia		Dysplasia		Carcinoma
	GST- ϕ (+)	GST- ϕ (-)	GST- ϕ (+)	GST-Π (-)	GST-Π (+)	GST- ϕ (-)	GST-Π (+)	GST-Π (-)
TA (+)	0	2	0	1	36	5	43	6
TA (-)	3	48	2	18	13	25	3	3

TA: telomerase activity. Expression of GST-Π correlated to that of telomerase activity in dysplasia and carcinoma (φ = 0.4831,P<0.00; φ = 0.3031, P<0.025 respectively); but there was no correlation between the expression of GST-Π and telomerase activity in normal epithelium and hyperplasia (P>0.05).