Copyright
©The Author(s) 2005.
World J Gastroenterol. Oct 14, 2005; 11(38): 6003-6008
Published online Oct 14, 2005. doi: 10.3748/wjg.v11.i38.6003
Published online Oct 14, 2005. doi: 10.3748/wjg.v11.i38.6003
Genotype | Controls | UC | CD | |||||
n1 | % | n1 | % | OR(95%CI)2 | n1 | % | OR(95%CI)2 | |
PTGS2.401 | ||||||||
A/A | 277 | 79 | 115 | 82 | 1 | 107 | 77 | 1.00 |
A/G | 66 | 19 | 24 | 17 | 0.82 (0.48 – 1.39)3 | 30 | 22 | 1.17 (0.70 –1.94)3 |
G/G | 7 | 2 | 1 | 1 | 1 | 1 | ||
Total | 350 | 100 | 140 | 100 | 138 | 100 | ||
PTGS2.926 | ||||||||
G/G | 256 | 75 | 112 | 81 | 1 | 106 | 76 | 1.00 |
G/C | 75 | 22 | 23 | 17 | 0.77 (0.47 – 1.28)3 | 31 | 22 | 1.06 (0.65 –1.73)3 |
C/C | 8 | 2 | 4 | 3 | 3 | 2 | ||
Total | 339 | 100 | 139 | 100 | 140 | 100 | ||
PTGS2.3050 | ||||||||
G/G | 250 | 71 | 109 | 75 | 1 | 102 | 71 | 1 |
G/C | 99 | 28 | 32 | 22 | 0.83 (0.52 – 1.32)3 | 38 | 26 | 0.97 (0.62 –1.53)3 |
C/C | 1 | 1 | 4 | 3 | 4 | 3 | ||
Total | 350 | 100 | 145 | 100 | 144 | 100 | ||
PTGS2.5209 | ||||||||
T/T | 265 | 75 | 110 | 76 | 1 | 95 | 66 | 1 |
T/G | 81 | 23 | 30 | 21 | 1.00 (0.62 - 1.61)3 | 46 | 33 | 1.63 (1.03 - 2.57)3 |
G/G | 7 | 2 | 5 | 3 | 2 | 1 | ||
Total | 353 | 100 | 145 | 100 | 143 | 100 | ||
PTGS2.8473 | ||||||||
C/C | 44 | 13 | 18 | 14 | 1.003 | 21 | 15 | 1.003 |
T/C | 147 | 42 | 49 | 34 | 54 | 38 | ||
T/T | 155 | 45 | 78 | 54 | 1.50 (1.00 - 2.27) | 68 | 47 | 1.10 (0.72 - 1.68) |
Total | 346 | 100 | 145 | 100 | 143 | 100 |
- Citation: Cox DG, Crusius JBA, Peeters PH, Bueno-de-Mesquita HB, Peña AS, Canzian F. Haplotype of prostaglandin synthase 2/cyclooxygenase 2 is involved in the susceptibility to inflammatory bowel disease. World J Gastroenterol 2005; 11(38): 6003-6008
- URL: https://www.wjgnet.com/1007-9327/full/v11/i38/6003.htm
- DOI: https://dx.doi.org/10.3748/wjg.v11.i38.6003