Copyright
©The Author(s) 2005.
World J Gastroenterol. Oct 14, 2005; 11(38): 5931-5937
Published online Oct 14, 2005. doi: 10.3748/wjg.v11.i38.5931
Published online Oct 14, 2005. doi: 10.3748/wjg.v11.i38.5931
Variables | n (n=32) | MMP-9 | P | iNOS | P | MVD | P | ||
+1 (n=25) | – (n=7) | + (n=23) | – (n=9) | (mean±SD) | |||||
Sex | |||||||||
Male | 24 | 20 | 4 | NS2 | 17 | 7 | NS | 68.50±17.38 | NS |
Female | 8 | 5 | 3 | 6 | 2 | 80.64±29.51 | |||
Age (yr) | |||||||||
>50 | 19 | 17 | 2 | NS | 16 | 3 | NS | 76.11±18.86 | NS |
≤50 | 13 | 8 | 5 | 7 | 6 | 64.86±23.35 | |||
Size of HCC (cm) | |||||||||
>5.0 | 21 | 19 | 2 | 0 | 17 | 4 | NS | 74.48±18.16 | NS |
≤5.0 | 11 | 6 | 5 | 6 | 5 | 62.91±20.63 | |||
Tumor capsule | |||||||||
Present integrally | 15 | 9 | 6 | 0 | 8 | 7 | 0.05 | 67.73±25.72 | NS |
Absent or not integral | 17 | 16 | 1 | 15 | 2 | 74.88±16.31 | |||
HbsAg3 | |||||||||
+ | 21 | 18 | 3 | NS | 16 | 5 | NS | 75.48±19.02 | NS |
– | 11 | 7 | 4 | 7 | 4 | 64.00±23.96 | |||
Cirrhosis | |||||||||
+ | 19 | 16 | 3 | NS | 15 | 4 | NS | 72.79±16.30 | NS |
– | 13 | 9 | 4 | 8 | 5 | 64.46±15.95 | |||
Ascites | |||||||||
+ | 6 | 4 | 2 | NS | 3 | 3 | NS | 64.83±22.73 | NS |
– | 26 | 21 | 5 | 20 | 6 | 73.08±20.99 | |||
Serum AFP4 (µg/L) | |||||||||
≤400 | 13 | 10 | 3 | NS | 11 | 2 | NS | 68.84±21.77 | NS |
>400 | 19 | 15 | 4 | 12 | 7 | 75.46±20.53 | |||
Histological grade | |||||||||
G1 | 17 | 12 | 5 | NS | 11 | 6 | NS | 65.94±19.14 | NS |
G2 | 9 | 7 | 2 | 6 | 3 | 73.56±20.97 | |||
G3 | 6 | 6 | 0 | 6 | 0 | 84.33±24.48 | |||
TNM stage | |||||||||
I–II | 16 | 9 | 7 | 0 | 9 | 7 | NS | 63.81±21.78 | 0.037 |
III | 16 | 16 | 0 | 14 | 2 | 79.25±18.08 | |||
Risk of recurrence | |||||||||
High-risk group | 18 | 18 | 0 | 0 | 17 | 1 | 0 | 82.56±17.29 | 0 |
Low-risk group | 14 | 7 | 7 | 6 | 8 | 57.36±17.19 |
- Citation: Sun MH, Han XC, Jia MK, Jiang WD, Wang M, Zhang H, Han G, Jiang Y. Expressions of inducible nitric oxide synthase and matrix metalloproteinase-9 and their effects on angiogenesis and progression of hepatocellular carcinoma. World J Gastroenterol 2005; 11(38): 5931-5937
- URL: https://www.wjgnet.com/1007-9327/full/v11/i38/5931.htm
- DOI: https://dx.doi.org/10.3748/wjg.v11.i38.5931