Focal adhesion kinase and Src phosphorylations in HGF-induced proliferation and invasion of human cholangiocarcinoma cell line, HuCCA-1

Figure 8 The HGF-mediated cell proliferation was not inhibited by 0. 1 µmol/L AZM555130 but was significantly inhibited by 0.5 and 1.0 µmol/L of AZM555130 for 25% and 34%, respectively. Without HGF, cell proliferation was inhibited by 0.1, 0.5, and 1.0 µmol/L of AZM555130 for 9%, 33%, and 41%, respectively. All values are mean±SE, ^aP < 0.05 and ^bP < 0.01, compared to the control in HGF-untreated cells; ^dP < 0.01, compared to the control in HGF-treated cells.