Effect of lysozyme chloride on betel quid chewing aggravated gastric oxidative stress and hemorrhagic ulcer in diabetic rats

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Oct 7, 2005 (publication date) through Apr 10, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Clinical Research

World J Gastroenterol. Oct 7, 2005; 11(37): 5853-5858
Published online Oct 7, 2005. doi: 10.3748/wjg.v11.i37.5853

Table 1 Gastric juice-aggravated various gastric biochemical parameters in stomachs of normal, DM and BQC fed DM rats

	Acid ack-diffusionμmol/stomach	Glutathioneμmol/gtissue	Lipid peroxidenmol MDA/gtissue	Mucusμg/gtissue	Hemoglobinmg/stomach	Ulcer areamm²/stomach
Normal saline
Control	8.6±1.2	3.8±0.4	45.6±4.2v	230.2±18.4	0.2±0.2	1.4±0.6
DM	5.0±0.8^a	2.4±0.3^a	95.4±5.2^a	186.1±10.2^a	2.2±0.5^a	64.6±8.5^a
BQC+DM	3.2±0.2^a	1.6±0.2^a	32±11.4^a	155.0±14.8^a	4.6±0.6 ^a	54.8±18.4 ^a
Gastric juice
Control	-164.2±5.4	3.4±0.2	54.0±7.8	220.0±14.5	0.6±0.2b	2.2±1.2
DM	-235.4±10.6^a^c	2.8±0.1^a^c	120.0±10.2^a^c	140.0±12.6^a^c	5.3±0.7^a^c	264.8±27.1^a^c
BQC+DM	-384.2±18.6^a^c	0.8±0.1^a^c	184.0±16.3^a^c	75.0±6.8^a^c	9.0±1.2^a^c	78.6±45.6^a^c

Data are mean±SE (n = 8).

^aP < 0.05 vs corresponding control group.

^cP < 0.05 vs corresponding group in saline-treatment. MDA = malondialdehyde, BQC = betel quid chewing, DM = diabetes mellitus.

Citation: Hung CR. Effect of lysozyme chloride on betel quid chewing aggravated gastric oxidative stress and hemorrhagic ulcer in diabetic rats. World J Gastroenterol 2005; 11(37): 5853-5858
URL: https://www.wjgnet.com/1007-9327/full/v11/i37/5853.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i37.5853