Significance and prognostic value of lysosomal enzyme activities measured in surgically operated adenocarcinomas of the gastroesophageal junction and squamous cell carcinomas of the lower third of esophagus

Table 3 Relative activities of lysosomal enzymes in adenocarcinoma of the GEJ and in squamous cell carcinoma of the LTE (mean±SE)

Enzymes	GEJ	LTE	Ratio of LTE/GEJ
	Tumor/own normal mucosa	Tumor/own normal mucosa
AGLU	0.91 ± 0.09	2.55 ± 0.78	2.8
AMAN	1.39 ± 0.12	2.36 ± 0.32	1.7
BGAL	1.33 ± 0.16	2.01 ± 0.42	1.5
CB	2.15 ± 0.34	4.89 ± 1.2	2.3
CL	1.48 ± 0.17	6.21 ± 2	4.2
DPP I	2.34 ± 0.52	12.43 ± 5.3	5.3
CH	1.3 ± 0.12	1.44 ± 0.31	1.1
DPP II	0.83 ± 0.08	1.39 ± 0.23	1.7
GCU	1.36 ± 0.24	1.46 ± 0.33	1.1
HEX	1.29 ± 0.18	2.06 ± 0.45	1.6
TPP I	1.66 ± 0.33	1.77 ± 0.21	1.1
THP	2.36 ± 0.41	3.59 ± 2.3	1.5

GEJ: gatroesophageal junction; LTE: lower third of the esophagus; SE: standard error; AGLU: α-glucosidase; AMAN: α-mannosidase; BGAL: β-galactosidase; CB: cathepsin B; CL: cathepsin L; DPP I: dipeptidyl-peptidase I; CH: cathepsin H; DPP II: dipeptidyl-peptidase II; GCU: β-glucuronidase; HEX: β-hexosaminidase B; TPP I: tripeptidyl-peptidase I; THP: thimet oligopeptidase.