1.5 Harmonic Imaging Sonography with microbubble contrast agent improves characterization of hepatocellular carcinoma

Figure 5 A 62-year-old man with C-type cirrhosis and HCC (18. 9 mm in diameter) in segment 4 of the liver. A: 1.5 Harmonic Imaging Sonography image obtained by real-time continuous sonography in the early phase (28 s after injection) shows abundant tumor vessels with peripheral branching; B: 1.5 Harmonic Imaging Sonography image obtained by real-time continuous sonography in the late phase (5 min after injection) shows residual enhancement of some tumor vessels, but the boundary between the tumor and the hepatic parenchyma is clearly depicted.