1.5 Harmonic Imaging Sonography with microbubble contrast agent improves characterization of hepatocellular carcinoma

Figure 4 A 78-year-old man with C-type cirrhosis and HCC (73. 3 mm in diameter) in the right liver. A: Right oblique conventional sonography image of the liver shows a mixed-pattern nodule 73.3 mm in diameter in segment 6 that exhibits the typical characteristics of HCC; B: 1.5 Harmonic Imaging Sonography image obtained by real-time continuous sonography in the early phase (20 s after injection) shows the tumor vessels; C and D: 1.5 Harmonic Imaging Sonography images obtained by real-time continuous sonography in the early phase, 28 s (C) and 32 s (D) after injection, show abundant tumor vessels with peripheral branching.