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©The Author(s) 2005.
World J Gastroenterol. Sep 28, 2005; 11(36): 5644-5650
Published online Sep 28, 2005. doi: 10.3748/wjg.v11.i36.5644
Published online Sep 28, 2005. doi: 10.3748/wjg.v11.i36.5644
Table 1 Overall expression of PLK1 in colon carcinoma as well as distribution of PLK1 expression in the study population, n (%)
| Characteristics | All cases | PLK1negative | PLK1positive | P | |
| All cases | 153 | 51 (33.3) | 102 (66.7) | ||
| Age (yr) | |||||
| ≤65 yr | 74 (48.4) | 28 (37.8) | 46 (62.2) | 0.3041 | |
| >65 yr | 79 (51.6) | 23 (29.1) | 56(70.9) | ||
| Dukes stage | |||||
| A | 35 (22.9) | 20 (57.1) | 15 (42.9) | ||
| B | 55 (35.9) | 19 (34.5) | 36 (65.5) | <0.0012 | |
| C | 50 (32.7) | 10 (20) | 40 (80) | ||
| D | 13 (8.5) | 2 (15.4) | 11 (84.6) | ||
| Tumor stage | |||||
| T1 | 10 (6.5) | 9 (90) | 1 (10) | ||
| T2 | 36 (23.5) | 14 (38.9) | 22 (61.1) | 0.0012 | |
| T3 | 96 (62.7) | 24 (25) | 72 (75) | ||
| T4 | 11 (7.3) | 4 (36.4) | 7 (63.6) | ||
| Nodal status | |||||
| N0 | 91 (59.5) | 38 (41.8) | 53 (58.2) | ||
| N1 | 30 (19.6) | 4 (13.3) | 26 (86.7) | 0.0492 | |
| N2 | 32 (20.9) | 9 (28.1) | 23 (71.9 | ||
| State of distant metastasis | |||||
| Mx | 140 (91.5) | 49 (35) | 91 (65) | 0.2211 | |
| M1 | 13 (8.5) | 2(15.4) | 11 (84.6) | ||
| Grade | |||||
| G1 | 6 (3.9) | 2 (33.3) | 4 (66.7) | ||
| G2 | 123 (80.4) | 43 (35) | 80 (65) | 0.4232 | |
| G3 | 24 (15.7) | 6 (25) | 18 (75) | ||
- Citation: Weichert W, Kristiansen G, Schmidt M, Gekeler V, Noske A, Niesporek S, Dietel M, Denkert C. Polo-like kinase 1 expression is a prognostic factor in human colon cancer. World J Gastroenterol 2005; 11(36): 5644-5650
- URL: https://www.wjgnet.com/1007-9327/full/v11/i36/5644.htm
- DOI: https://dx.doi.org/10.3748/wjg.v11.i36.5644