Synergistic effect of bromocriptine and tumor necrosis factor-α on reversing hepatocellular carcinoma multidrug resistance in nude mouse MDR1 model of liver neoplasm

Table 2 Volume and size of orthotopic tumor tissues (mean±SD)

Groups	Mice and incidenceof tumor, n (%)	Volume(cm3)	Rate of volumeinhibition (%)	Weight(g)	Rate of weightinhibition (%)
HepG2			57		54
Experiment	8 (100)	1.25 ± 0.13		0.72 ± 0.12
Control	8 (100)	2.92 ± 0.21		1.55 ± 0.17
ADM			14		18
Experiment	8 (100)	2.03 ± 0.11		1.22 ± 0.11
Control	8 (100)	2.37 ± 0.18		1.48 ± 0.21
TNF			58a		57
Experiment	8 (100)	0.67 ± 0.22		0.45 ± 0.16
Control	8 (100)	1.37 ± 0.18		0.93 ± 0.18
BCT			66c		67
Experiment	8 (100)	0.49 ± 0.17b		0.29 ± 0.21
Control	8 (100)	1.45 ± 0.26		0.88 ± 0.17

^aP>0.05 vs HepG₂ group, χ² = 4.32;

^bP<0.01 vs ADM group, t = 2.38;

^cP<0.05 vs HepG₂ group, χ² = 2.49.