DNA ploidy analysis and expression of MMP-9, TIMP-2, and E-cadherin in gastric carcinoma

Table 2 Relationships between expression of MMP-9, TIMP-2 or E-cadherin, and clinical features in gastric carcinoma

	n	Positive		TIMP-2	Rate (%)		P
		MMP-9	P		P	E-cadherin
Tumor size
5 cm	53	66.0	>0.05	41.5	>0.05	39.6	>0.05
<5 cm	46	67.4		45.7		45.7
LN metastasis
Negative	46	54.3	<0.01	56.5	<0.05	54.3	<0.05
Positive	53	79.2		32.1		32.1
Metastasis
Primary carcinoma	99	66.7	<0.05	43.4	>0.05	42.4	>0.05
Metastatic LN	25	92.0		36.0		20.0
Metastatic carcinoma	16	81.7		43.8		37.5
Depth of invasion
Submucosa	7	28.6c	<0.05	71.4c	<0.05	85.7c	<0.05
Superficial muscular layer	27	59.3		59.3		48.1
Deep muscular layer or serosa	65	73.8		33.8		35.4
TNM stage
Stage II	8	37.5e	<0.05	50.0	>0.05	62.5	>0.05
Stage III	16	50.0		43.8		50.0
Stage IV	75	73.3		42.7		38.7

^cP<0.05 vs deep muscular layer or serosa;

^eP<0.05 vs stage IV.