DNA ploidy analysis and expression of MMP-9, TIMP-2, and E-cadherin in gastric carcinoma

Table 1 Relationship between expression of MMP-9, TIMP-2 or E-cadherin, and histopathological features in gastric carcinoma

	n	Positive		TIMP-2	Rate (%)		P
		MMP-9	P		P	E-cadherin
Differentiation
Well	16	50	>0.05	62.5	>0.05	75	<0.01
Moderate	18	66.7		55.6		61.1
Poor	36	69.4		38.9		30.6
Signet ring cell type	29	72.4		31		27.6
Tumor recurrence
Primary carcinoma	91	65.9	>0.05	44	>0.05	44	>0.05
Recurrent carcinoma	8	75		37.5		25
Carcinoma and non-neoplastic
Gastric carcinoma	99	66.7	<0.01	43.4	>0.05	42.4	<0.001
Non-neoplastic gastric mucosa	16	31.3		31.3		87.5
Lauren’s classification
Intestinal type	67	58.2a	<0.05	46.3	>0.05	53.7a	<0.05
Diffuse type	22	90.9		36.4		13.6
Mixed type	10	70		40		30
Borrmann’s classification
Types I–II	9	33.3c	<0.05	66.7	<0.05	55.6c	<0.05
Type III	70	65.7		47.1		42.9
Type IV	20	85		20		25

^aP<0.05 vs diffuse type;

^cP<0.05 vs type IV.