Porcine acute liver failure model established by two-phase surgery and treated with hollow fiber bioartificial liver support system

Table 1 Biochemical indexes of ALF pigs at different time points (mean±SD)

	0 h	1 h	3 h	5 h	7 h	9 h	11 h	13 h
ALT (nkat/L)	4.7±0.7	5.1±1.3	4.9±1.2	5.2±1.5	7.6±1.8a	8.2±2.1a	10.9±3.4a	16.2±1.2a
AST (nkat/L)	18±1	19±1	20±1	25±2	40±5a	113±22a	30±8a	10±4a
Tbil (μmol/L)	40±6	44±9	41±7	47±10	55±8a	49±8a	52±5a	59±10a
Alb (g/L)	36±5	33±4	31±4	30±4	28±3	27±4a	27±3a	25±4a
Amm (μmol/L)	117±18	215±29	269±37a	285±34a	275±30a	239±28a	216±19a	280±35a
BUN (mmol/L)	2.7±0.6	2.8±0.4	2.5±0.4	2.5±0.6	2.8±0.5	2.8±0.4	2.9±0.5	3.5±0.9a
Cr (μmol/L)	74±8	77±7	77±9	64±5	63±7	87±9a	102±17a	98±10a
PT (s)	12.8±1.0	13±1.1	14.4±1.4	15.4±1.8	17.5±1.7a	19.2±1.9a	21.3±1.9a	21.9±2a
Fib (g/L)	2.2±0.2	2.1±0.2	1.9±0.2	1.5±0.2a	1.2±0.2a	0.8±0.1a	0.8±0.1a	0.7±0.1a

^aP<0.05 vs 0 h group.